Description
In this presentation, Karen Costenbader discusses the epidemiology of cardiovascular disease (CVD) in lupus patients, highlighting their heightened risk compared to the general population. Costenbader outlines how CVD is the leading cause of death in lupus, particularly in young women, referencing seminal studies that indicate young women with lupus have over a 50-fold increased risk of myocardial infarctions compared to healthy populations. She delves into recent data showing that cardiovascular mortality rates in lupus patients have not improved over the past two decades, despite reductions in mortality rates for other diseases like rheumatoid arthritis.
Costenbader introduces various cardiovascular risk prediction models, emphasizing that traditional algorithms, such as the Framingham risk score, significantly underestimate CVD risk in lupus patients due to neglected lupus-specific inflammatory factors. She discusses the development of the lupus SLECRISK tool, designed to predict 10-year CVD risk by integrating traditional risk factors with lupus-specific ones, and shares results indicating that the tool has greater sensitivity and accuracy than existing models. Throughout the talk, Costenbader stresses the importance of patient-specific assessment and the need for improved healthcare strategies tailored to the unique risks faced by lupus patients.
Part of: Surgical Techniques and Training Collection
"SLE Cardiovascular Disease" is included in the following Surgical Techniques and Training playlist: