Does TKA Alter Synovial Fuid Properties A Comparison of Necropsy TKA and Contralateral Specimens

Description

In this presentation, Bailey Bond, a participant in the joint biomedical engineering program at the University of Tennessee Health Science Center and Memphis, explores whether total knee arthroplasty (TKA) affects synovial fluid properties. Bond outlines the background of the study, including the prevalence of aseptic lesions in revision TKAs and the interaction of synovial fluid with metal ions from implants. The research aims to determine if physical and chemical properties, like fluid volume and pH, differ between TKA and contralateral knee specimens, and how these differences may impact the electrochemical properties of the synovial fluid.



The methodology involves analyzing 15 pairs of necropsy specimens, measuring fluid volume and pH, followed by electrochemical testing using open circuit potential and electrochemical impedance spectroscopy. Results indicate that TKA specimens have significantly higher synovial fluid volume and instantaneous corrosion rates compared to contralateral knees, while pH differences were not significant.



Bond concludes by emphasizing the study's aim, the findings, and plans for future research to include a larger sample size and alternative circuit models to validate results. Special thanks were given to collaborators and supporting institutions.

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